Research
The world has realised the miracles of Genetic Engineering in agriculture – higher yield and better varieties of crops; in medicine – diagnostics and cures that were only a dream a few years back. The department has developed state of the art research facilities, and several of our faculty members have very productive national and international research collaborations. The department dramatically prioritises externally funded research projects from India and abroad. Collaborative and interdisciplinary research is active in genomics, cancer biology, applied microbiology, bio-energy, plant, animal and microbial genetics. The department is dedicated to impact-making biological discoveries and vital research publications. The department has identified a few focus areas in which it possesses strong representation and leadership – Genomics, Cancer Biology, Microbiology and Integrative Biology. Some of the essential facilities available in the department are the transgenic greenhouse facility, automated DNA sequencing platforms, biological mass spectrometry facility, zebrafish facility, fluorescence spectroscopy, light microscopy facility, gene pulser, etc.
exciting research activities in the department
- Identification of disease-causing mutations by next-generation sequencing
- Gene editing in zebrafish and ricey
- Whole-genome and whole-exome sequencing
- Recombinant expression of pharmaceutical proteins in plants
- DNA barcoding of Indian medicinal plants
- Ultrastructural and biomechanical changes in metastatic tumour cells
- RNAseq data analysis using molecular interaction network-based approaches
- Understanding the interactions of a membrane protein with the lipid bilayer
- Targeting cancer stem cells
- Isolation of antimicrobial peptides from marine sources
- KISS1 regulation of notch signalling in melanoma
- Zebrafish cancer models
- Isolation and characterisation of stem cells from human dental pulp
- Signalling pathways in oral squamous cell carcinoma
- Developing point of care diagnostic kits for infectious diseases
- Metabolic engineering of Clostridium spp for enhancing solvent production
- Exosome engineering and exosome biology research
- Genotyping for the polycystic ovarian syndrome (PCOS)